Helicobacter pylori, a solution without antibiotics

Popular Science

Some people infected with Helicobacter pylori (HP) experience no symptoms ; others develop excessive stomach acid, complicated by pyloric gastritis and duodenal ulcers . Still others develop chronic gastritis , increasing their risk of stomach cancer. If H. pylori can be eradicated , the chance of ulcer recurrence drops from 50% to 10%.

👉 In fact , more than 90% of duodenal ulcers and about 80% of gastric ulcers are related to Helicobacter pylori infection!
If you or your family members have the following conditions, you should actively seek medical examination and treatment:
• Gastric or duodenal ulcer • Chronic gastritis, gastric mucosal erosion
• Stomach cancer or family history • Symptoms such as indigestion, bloating, and acid reflux • Diagnosed with MALT lymphoma

Research has found that children aged 3-5 are more susceptible to Helicobacter pylori infection. HP infection can affect development and may lead to growth retardation, iron deficiency anemia, otitis media, and other problems. (Source: Berlin Child Research Center, Berlin Medical University)

In a study of indigenous people in Colombia, it was found that children aged 4-8 years who were infected with Helicobacter pylori grew more slowly than children who were not infected. In addition to the conventional risks, children infected with Helicobacter pylori are more likely to suffer from diseases such as slow growth, iron deficiency anemia, and idiopathic thrombocytopenic purpura.

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How do I know if I am infected?

Have points "Trespassing" and "non-trespassing". There are three main types of non-invasive methods:

• C13-urea breath test: This is the most commonly used method in hospitals to detect Helicobacter pylori. It measures the C13 content in the patient's breath to detect the presence of Helicobacter pylori.
• Serum antibody test: A blood sample is drawn to determine if there are antibodies to Helicobacter pylori in the serum. The presence of antibodies indicates past or current infection with Helicobacter pylori.
• Fecal antigen assay: This method uses enzyme immunoassay to detect Helicobacter pylori antigen in feces. This method is simple and safe because it only requires the collection of feces.
• Simple test strips are available on the market that collect plaque and can be used by the whole family. Contact our customer service for free test strips if needed.

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Traditional treatments hit a bottleneck?

The most common method to treat Helicobacter pylori is the "three-in-one therapy": stomach medicine + two antibiotics.
Several common bottlenecks in traditional therapies:
1. Drug resistance increases, efficacy becomes unstable, and many people experience side effects (such as diarrhea, bloating, and loss of appetite).
2. For the elderly or children, high-intensity antibiotic therapy can overwhelm the body, killing off all beneficial bacteria and prolonging the recovery period.

Probiotics are the hidden god teammate for gastric health, Pylopass patented bacteria!

💡 At this time, probiotics specifically targeting Helicobacter pylori become another gentle choice!

Studies have shown that probiotics can increase the eradication rate of Helicobacter pylori, reduce side effects, and even strengthen overall gastrointestinal health!
Nutrimexx was developed in 1997 by German pharmacist Mr. Freud. He carefully selected over 700 strains of Lactobacillus and ultimately identified a specific strain, Pylopass, that cross-links with Helicobacter pylori. The "cross-linking degree" refers to the degree to which the Pylori bacteria physically bind together to eliminate harmful bacteria. The higher the degree of cross-linking, the better, resulting in a continuous elimination of Helicobacter pylori.

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Several advantages of probiotics in fighting Helicobacter pylori

1️⃣ Physical package handling stabilizes the gastric mucosa and builds a protective wall

Probiotics like Lactobacillus strengthen the gastric mucosa, making it less susceptible to invasion by harmful bacteria, like a layer of "bulletproof vest." Probiotics release natural antibacterial compounds like organic acids, short-chain fatty acids, and bacteriocins, which directly interfere with the survival environment and enzyme activity of Helicobacter pylori.

2️⃣Regulate inflammatory response and relieve discomfort

For example, Lactobacillus reuteri can preemptively adhere to the stomach wall, competing with Helicobacter pylori for territory and reducing its colonization rate. Probiotics can also help reduce the immune inflammatory response induced by Helicobacter pylori, alleviating symptoms such as stomach redness, swelling, pain, and acid reflux.

3️⃣ Stabilize intestinal flora and reduce side effects

Antibiotics often cause an imbalance in the intestinal flora, leading to diarrhea and flatulence. Probiotic supplementation can restore intestinal stability and facilitate overall treatment.

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The most powerful DSM17648 ( Lactobacillus reuteri) probiotics

Let the data speak for itself: How effective is Reuteria reuteri against P.

🔹 Clinical Trial 1:

Study Design: To explore the efficacy and safety of probiotic treatment. Twenty-seven patients with asymptomatic Helicobacter pylori infection (including twins and only children) were included. A 14-day single-blind, placebo-controlled trial was conducted in twins (divided into probiotic group and placebo group) In only children, a single-blind, nonrandomized crossover design (14 days of placebo followed by 14 days of probiotic treatment) was used. 1 9 C urea breath test (UBT) was performed to detect Helicobacter pylori infection at baseline, after placebo treatment, after probiotic treatment, and 4-6 weeks after the end of the intervention. The results showed that Lactobacillus reuteri DSM 1 7 6 4 8 preparation can significantly reduce the Helicobacter pylori infection Helicobacter pylori infection level and good safety

Sources: Holz, C, Busjahn, A, Mehling, H, Arya, S, Boettner, M, Habibi, H,
& Lang, C.Significant reduction in Helicobacter pylori load in humans
Lactobacillus reuteri DSM17648: a pilot study. Probiotics and
antimicrobialproteins, 2015, 7(2): 91-100.

🔹 Clinical Trial 2:

Study design: To explore the effectiveness and safety of probiotic treatment in reducing the severity of HP infection and improving gastrointestinal symptoms in infected patients. Twenty-four HP-infected patients with mild dyspepsia were enrolled in the study. They received a placebo for the first four weeks (days 1-28) and a probiotic solid tablet for the next four weeks (days 29-56). HP burden was assessed using a C urea Breath Test (UBT) at baseline, day 28, and day 56. Changes in gastrointestinal symptoms were assessed using the Gastrointestinal Symptom Rating Scale (GSRS). Blood samples were also collected to assess changes in physiological parameters related to safety. The results showed that the Lactobacillus reuteri DSM 17648 preparation had the potential to inhibit HP infection and improve HP-related gastrointestinal symptoms, and had good safety.

Source: Buckley M, Lacey S, Doolan A, et al. The effect of Lactobacillus
reuteri supplementation in Helicobacter pylori infection: a placebocontrolled,
single-blind study. BMC nutrition, 2018, 4(1): 1-8.

🔹 Clinical Trial 3:

Study design: Double-blind, randomized, placebo-controlled trial, enrolling 103 children aged 9-17 years with Helicobacter pylori infection and chronic gastritis. They were randomly divided into a probiotic group, a treatment placebo group (quadruple therapy + placebo group), and a combined treatment group (probiotic + quadruple therapy). All groups were further divided into two subgroups (28 days and 56 days) according to the duration of probiotic/placebo treatment. At the beginning and end of the trial (day 0 and day 56), all children underwent upper laparoscopy, and 4 upper cavity and gastric body biopsy specimens were obtained, followed by histological examination and rapid urease test. Conclusion: In children with HP-related chronic gastritis, Lactobacillus reuteri alone DSM 1 7 6 4 8 preparations, its eradication rate is close to that of quadruple therapy and can effectively improve symptoms: Combination therapy can further increase the eradication rate (9%) and reduce the side effects of four-in-one therapy.

Data cited from: Kornienko EA, Parolova NI, Ivanov SV, Polev DS, Zykin PA, Kondratenko YD, Zakharchenko MM,
Gastric microbiota and probiotics opportunities in helicobacter pylori eradication in children.
Gastroenterol Hepatol Open Access, 2020, 11(1): 13-23.

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💡Probiotics = The key assist in treating Helicobacter pylori!

• Product: Nutrimexx perfect life Pylomed Akut anti-Helicobacter pylori chewable tablets 60 tablets • Accurate: Non-antibiotic method to eliminate Helicobacter pylori, protect good bacteria and eliminate bad bacteria. • Effective: When used continuously for more than 8 weeks, the HP eradication effect is close to that of antibiotic treatment. • Safe: No side effects, no drug resistance, gluten-free, lactose-free, fructose-free. • Convenient: Chew and eat, inactivated freeze-dried strain, no need for refrigerated storage, stable quality. • Combined use: When used with four drugs, it can reduce side effects and increase the eradication rate. • Purity: Contains only pylopass patented strains and xylitol filler, effective and direct • Taste: Lemon mint flavor , fresh breath, high compliance.

• Product: Nutrimexx Pylomed Mini for Kinder Kautabletten 60 Helicobacter pylori mini chewable tablets for children • Accurate: Non-antibiotic method to eliminate Helicobacter pylori, protect good bacteria and eliminate bad bacteria. • Effective: When used continuously for more than 8 weeks, the HP eradication effect is equivalent to that of the quadruple combination. • Safe: No side effects, no drug resistance, gluten-free, lactose-free, fructose-free. • Convenient: Chew and eat, inactivated freeze-dried strain, no need for refrigerated storage, stable quality. • Taste: Cherry flavor , sweet and sour. • Purity: Contains only pylopass patented strains and xylitol filling, effective and direct

Don’t think that taking medicine is foolproof anymore - the current trend is to use a "dual approach of medicine + bacteria" to have a higher success rate!

🟠 If you are currently being treated for Helicobacter pylori, don't forget to discuss with your doctor whether to take probiotics with you. 🟠 Choose probiotics that are scientifically based, clearly labeled with strains, and in adequate dosage. 🟠 Products containing patented Lactobacillus, Bifidobacterium, and Saccharomyces boulardii are especially recommended.

Protecting your stomach’s health doesn’t just depend on medication; probiotics can also help!

Sources:

1. Health Net: Helicobacter pylori drug resistance: A doctor reveals a "new solution" to combat bacteria with bacteria (February 29, 2024)

2. Xiong Jingjing, Huang Yongkun. Application of probiotics in preventing Helicobacter pylori infection in children[J]. Journal of Chinese Journal of Edible Pediatrics, 2017, 32(2): 106-110.